why diabetes nephropathy patients have more nocturia

Why diabetes nephropathy patients nocturia more? Impairment of renal function in diabetic patients, diabetic nephropathy patients with nocturia more is a very common phenomenon, especially in elderly patients with diabetes mellitus and diabetic patients for more than a decade. This is all decreased renal tubular function.
Among them, the water back to absorb the main in the distal renal tubules, when distal renal tubular damage, patients with urine concentration function decline, and low osmotic pressure, the low proportion of urine.
Diabetic nephropathy patients nocturia more, then, what should be check. Diabetes patients with nocturia more than 12 hours can check urine osmotic pressure and urine specific gravity water bans, glycosuria, urine volume (the ratio of day and night) CCr. As curative effect judgment standard, in addition to the 12 hour urine osmotic pressure and urine specific gravity, water, renal tubular marker protein such as urine creatinine clearance a1 - b2 - MG MG, urine and urine NAG can be reference.
The mechanisms of diabetic renal tubular damage and metabolic disorders such as diabetes, blood state of high permeability, high adhesion, microvascular injury, and high glomerular filtration, high perfusion state, etc, all can make abnormal renal tubular structure, the structure of the anomaly is bound to lead to kidney damage. Renal tubular's main function is to absorb glomerular filtration of liquid electrolyte, protein and most of the water, adjust the pH of urine, diluted and concentrated urine, etc.