why nephrotic syndrome patients have different symptoms

1 proteinuria: When the glomerular filtration membrane molecules barriers and charge barrier (especially the charge barrier) is damaged, the glomerular filtration membrane on plasma proteins (right mainly to albumin) permeability increase, resulting in increased urine protein content, when more than distal convoluted tubule back absorption, the formation of massive proteinuria.
2 changes in plasma protein: a large loss of albumin in the urine, and promote compensatory albumin synthesis in the liver. When the liver albumin synthesis increases sufficient to overcome the lost, then there hypoalbuminemia, in addition, because of gastrointestinal mucosal edema resulting loss diet, protein intake, malabsorption or lost is hypoalbuminemia causes.
3 edema: hypoalbuminemia the plasma colloid osmotic pressure, water from the intravascular space into the tissue and is the main reason for edema.
4 hyperlipidemia: high cholesterol and (or) hypertriglyceridemia, serum LDL, VLDL, and lipoprotein (a) concentrations increased, often coexist with hypoalbuminemia. The pathogenesis of hepatic synthesis of lipoproteins and lipoprotein increased decomposition of weakening.